Cyclophosphamide interactions
WebSep 21, 2024 · Cyclophosphamide interferes with oogenesis and spermatogenesis. It may cause sterility in both sexes. Development of sterility appears to depend on the dose of cyclophosphamide, duration of therapy, and the state of gonadal function at the time of treatment. Cyclophosphamide-induced sterility may be irreversible in some patients. WebCyclophosphamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: nausea vomiting loss of appetite or weight abdominal pain diarrhea hair loss sores on the mouth or tongue changes in skin color changes in color or growth of finger or toe nails Some side effects can be serious.
Cyclophosphamide interactions
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WebClinically significant pharmacokinetic interactions between aprepitant/fosaprepitant and bosutinib PO, cabazitaxel IV, cyclophosphamide IV, dexamethasone PO, methylprednisolone IV, midazolam PO/IV, oxycodone PO and tolbutamide PO were identified, as were adverse events resulting from an interaction between … Web4 rows · Cyclophosphamide Disease Interactions. There are 6 disease interactions with cyclophosphamide. ...
WebDec 4, 2012 · Serious side effects can occur with cyclophosphamide use. See "Drug Precautions" section. Other less serious, more common side effects include: nausea vomiting loss of appetite weight loss stomach pain diarrhea temporary hair loss mouth sores changes in skin or nail color menstrual changes temporary or permanent sterility WebAmong direct oral anticoagulants, a theoretical interaction between aprepitant and rivaroxaban or apixaban exists. Interactions between aprepitant and quetiapine or diltiazem or sirolimus required dose reductions to avoid adverse outcomes. The intravenous route had a weaker inhibitory effect on CYP3A4 than the oral pathway.
Webyou should know that cyclophosphamide may interfere with the normal menstrual cycle (period) in women and may stop sperm production in men. Cyclophosphamide may … WebCyclophosphamide may be associated with certain side effects which include the following: Nausea Vomiting loss of appetite Stomach ache Diarrhea Darkening of skin and nails Although most of these disturbances are temporary, nausea and vomiting can be severe and the resulting dehydration can be very serious.
WebFeb 17, 2024 · Mechanism of Action. Cyclophosphamide is an alkylating agent that prevents cell division by cross-linking DNA strands and decreasing DNA synthesis. It is a …
WebCyclophosphamide has the following interaction information: Drug interaction information Severe interactions are highlighted with a red marker. Find out more about BNF … legal seminars in michiganWebJul 1, 2012 · The authors hypothesized that this interaction was related to the autoinduction of cyclophosphamide, which usually occurs within 24 hours of cyclophosphamide administration. Changes in cyclosporine levels will occur fairly rapidly when the two drugs are used concurrently. legal sense townsvilleWebDec 19, 2010 · drug interactions lead to altered concentrations of a drug or its metabolites resulting from changes in absorption, distribution, metabolism, or elimination. Interactions between two or more drugs may affect any of the stages of drug metabolism. The most common sites of interaction are in the intestinal lumen and liver during CYP450 … legal selling of t shirtsWebDec 24, 2009 · Such is the case with the interaction between voriconazole and phenytoin: voriconazole levels can be reduced by 49% and phenytoin levels increased by 67%. 51 The enzymes involved are CYP 3A4 and CYP 2C19. Careful monitoring of both drug levels is recommended when these two drugs are given together. Warfarin is a CYP 2C9 substrate. legal separation agreement bcWebJul 4, 2024 · National Center for Biotechnology Information legal sentiment analysisWebApr 1, 2024 · Infection—May decrease body's ability to fight infection. Kidney disease—The effects of cyclophosphamide may be increased because of slower removal from the … legal separation agreement in michiganWebSep 18, 2024 · lower back or side pain. missing menstrual periods. painful or difficult urination. With high doses and/or long-term treatment. Blood in the urine. dizziness, … legal separation agreement in florida