2024 Emp2 antibody

Emp2 antibody

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August undefined, 2024

WebA synthetic peptide of human EMP2 is used for rabbit immunization. Conjugate Unconjugated Target Alternative Names EMP2; epithelial membrane protein 2; XMP; EMP-2; MGC9056; Entrez Gene ID 2013 UniProt ID P54851 Product Background Antigen Description Epithelial membrane protein 2 is a protein that in humans is encoded by the … WebMay 15, 2012 · When the EMP2 levels in response to treatment with the anti-EMP2 antibody fragment was monitored, the EMP2 levels on the HEC1A/EMP2 cell surface were notably reduced within 24 h relative to the negative control cells treated with the A10 isotype control diabody (Fig. 3b). These results suggested that binding of anti-EMP2 antibody …

EMP2 - Antibodies - The Human Protein Atlas

WebFeb 20, 2013 · Endometrial membrane protein-2 (EMP2) is a member of the growth-arrest specific protein 3/peripheral myelin protein 22 family of proteins, which are believed to play a role in the development of endometrial cancer in women (1). In addition, overexpression of EMP2 in endometrial cancer is considered to predict a negative outcome for the patient … Web13731 Ensembl ENSG00000213853 ENSMUSG00000022505 UniProt P54851 O88662 RefSeq (mRNA) NM_001424 NM_007929 RefSeq (protein) NP_001415 NP_031955 … solidworks flow simulation thermal

Epithelial membrane protein 2 (EMP2): A systematic review of its ...

WebEMP2 Antibody (NBP3-17361): Novus Biologicals View Rabbit Polyclonal anti-EMP2 Antibody (NBP3-17361). Validated Applications: IHC, IHC-P. Validated Species: Human. Skip to main content Support: 1-888-506-6887 Items in Cart (0) [X] Quick Order Account COVID-19 Research Tools Antibodies Primary Antibodies Conjugated Antibodies WebSpecificity： This EMP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the C-terminal region of human EMP2. Dilution： WB,1:1000;IHC-P,1:10~50; Purification： Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This WebBiochem/physiol Actions. Epithelial membrane protein-2 (EMP2) is a member of the four transmembrane superfamily (TM4SF) and is thought to mediate trafficking of diverse … solidworks floxpress 進まない

Rabbit Anti-Human EMP2 (aa99-129) [119-17279]

Rabbit Polyclonal Anti-EMP2 Antibody - Atlas Antibodies

http://www.biodragon.cn/plus/pdf.php?aid=117562 WebJun 12, 2024 · Anti-EMP2 IgG1 reduced the expression and activity of ALDH and correspondingly reduced both primary and secondary tumor load. Our results collectively suggest that anti-EMP2 therapy may be a... solidworks flow simulation 境界条件WebEpithelial membrane protein-2 (EMP2) is a member of the four transmembrane superfamily (TM4SF) and is thought to mediate trafficking of diverse proteins such as alpha6beta1 integrin and MHC class I to lipid raft microdomains. EMP2 has also recently been recognized as a putative tumor suppressor gene in certain model systems. Sequence solidworks flow simulation validation

"WebAnti-EMP2 antibody (ab223718) at 1/250 dilution + MCF7 (human breast adenocarcinoma cell line) cell lysate Predicted band size: 19 kDa. Immunocytochemistry/ … " - Emp2 antibody

Emp2 antibody

EMP2 - Antibodies - The Human Protein Atlas

WebAbcam - antibodies and reagents supplier, find any antibody Hello. We're improving abcam.com and we'd welcome your feedback. ... Anti-EMP2 antibody - C-terminal (ab174699) Description: Rabbit polyclonal to EMP2 - C-terminal. Application: IHC-P, WB. Reactivity: Mouse, Human. Conjugate: Unconjugated. WebJun 12, 2024 · To determine if antibody targeting could produce a similar effect, HEC1A/EMP2 or HEC1A/VC cells were incubated with control IgG1 or the anti-EMP2 IgG1 overnight in a hypoxic chamber.

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WebEpithelial membrane protein 2 (EMP2) is a cell surface protein that has recently emerged as an object of neuro-oncological interest due to its potential to be utilized as a biomarker … WebApr 6, 2014 · Importantly, no change in cellular viability was measured in EMP2-negative HS578t cells even at high concentrations of the antibody. As anti-EMP2 IgG1 recognized murine EMP2, we determined if the antibody could elicit a similar response in the 4T1 mouse mammary tumor line. 4T1 cells were susceptible to anti-EMP2 IgG1 with an IC 50 …

WebJan 1, 2024 · Anti-EMP2 monoclonal antibody significantly reduced tumor growth in mice, suggesting involvement of EMP2 in stemness of breast cancer. Bladder: Li et al., 2015 43: Urothelial carcinoma: EMP2 suppressed cell cycle progression through regulation of G2/M checkpoint and can be a prognostic factor in bladder cancer patients. WebUseful information about the protein provided by UniProt. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role i n regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the ...

WebJan 2, 2024 · As the antibody-antigen complex rapidly internalizes, we have created an anti-EMP2 drug conjugate to improve on the efficacy of the naked antibody. Our second generation antibody includes the toxin monomethyl auristatin (MMAE), a potent microtubule-disrupting toxin, conjugated to the fully human anti-EMP2 IgG1 through both … WebNov 7, 2024 · HOUSTON-- ( BUSINESS WIRE )--OncoResponse today announced that it has closed the acquisition of Paganini Biopharma, acquiring all of its assets including an anti-epithelial membrane protein 2...

WebTo test the hypothesis that EMP2 may be a suitable target for therapy, we constructed a fully human immunoglobulin G1 (IgG1) antibody specific for a conserved domain of human …

WebKey features and details Rabbit polyclonal to EMP2 Suitable for: ICC/IF, IHC-P, WB Reacts with: Human Isotype: IgG You may also be interested in Protein Recombinant Human EMP2 protein (ab152364) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) Primary Anti-CD68 antibody [KP1] (ab955) View more associated products Overview Product name solidworks flow simulation 使い方WebInvitrogen Anti-EMP2 Polyclonal, Catalog # PA5-42011. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody reacts with Human samples. Supplied as 100 µL purified … solidworks floxpress 使い方 solidworks floxpress 产品代码WebJan 27, 2015 · Immunocytochemistry/ Immunofluorescence: EMP2 Antibody [NBP1-86847] - Staining of human cell line U-251 MG shows … solidworks floxpressWebAs a proof of principle to determine whether EMP2 could serve as a target for therapy, cells were treated using specific anti-EMP2 antibody reagents. These reagents were effective in killing GBM cells in vitro and in reducing tumor load in subcutaneous mouse models. small arms bullet trapWebJan 15, 2024 · Results: Anti-EMP2 antibody, compared to control antibody or vehicle, significantly reduced neovascularization as measured by clinical score and central cornea thickness, as well as by histologic ... small arms by countryWebJun 9, 2024 · This first three anti-EMP2 antibody treatments were administered as 10 mg/kg body weight of mouse and last three anti-EMP2 treatments were 20 mg/kg body weight of mouse. Bioluminescence images were captured on days 1, 7, 14 and 21 post tumors implantation to monitor tumor growth. A two-way analysis of variance was used to … small arms cartridge brass