WebTrial Summary FINEARTS-HF: Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40% WebAdditional clinical trials are underway and will help define the role of finerenone in other disease states; these include FINEARTS-HF in patients with HF and LVEF of ≥40%, FIND-CKD in patients with non-diabetic CKD, and CONFIDENCE in patients with CKD in …
A randomized controlled study of finerenone vs. eplerenone
WebMar 11, 2014 · The Candesartan in Heart failure Assessment of Reduction in Mortality and morbidity (CHARM Preserved) trial included 3023 patients with an EF >40% 31 and compared Candesartan, uptitrated to 32 mg/day to placebo (Pbo). This trial failed to demonstrate a significant benefit on CV mortality, whereas a reduction in HF … http://mdedge.ma1.medscape.com/jcomjournal/article/240253/arrhythmias-ep/fidelio-dkd-finerenone-cuts-new-onset-afib-patients-type-2 daniela schettino ginecologo torino
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WebMay 18, 2024 · A prespecified, exploratory analysis from the FIDELIO-DKD trial showed that the nonsteroidal MRA finerenone significantly cut new-onset AFib. WebJul 14, 2016 · The finding of reduced clinical events in the finerenone 10→20 mg group should be further explored in a large outcomes trial. Finerenone was well tolerated and … WebApr 12, 2024 · In June 2024, Bayer announced the initiation of the FINEARTS-HF study, a multicenter, randomized, double-blind, placebo-controlled Phase III study which will … daniela schettini