Foxm1b
WebFOXM1B expression in the livers of older transgenic mice restore hepatocyte DNA replication rates to the higher rate present in young livers. FOXM1B activates the transcription of cyclin B1, cyclin D1 and Cdc25B. REFERENCES 1. Ye, H., et al. 1997. Hepatocyte nuclear factor 3/fork head homolog 11 is WebJan 31, 2013 · FOXM1b exhibited a transforming potential 10-fold greater than that of FOXM1c (Figure 1B ). FIGURE 1 FIGURE 1. FOXM1b has higher expression levels and transforming potential in cancer cells. (A) …
Foxm1b
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WebNov 1, 2014 · It has been suggested that FOXM1b is present in the predominant species of cancer cells and has a greater transforming potential compared with FOXM1c [3]. FOXM1 has a vital role in embryonic development, adult tissue homeostasis, cancer initiation and progression [4]. It regulates a broad spectrum of normal essential biological functions ... WebApr 7, 2024 · FoxM1 is a pro-proliferation transcription factor. It stimulates expression of genes important for G1 to S progression, as well as mitotic …
WebSep 18, 2003 · FoxM1B (previously named HFH-11, WIN or Trident) is a member of the Forkhead box (Fox) transcription factor family, whose members play important roles in regulating embryogenesis, cellular... WebNov 1, 2014 · FOXM1: An emerging master regulator of DNA damage response and genotoxic agent resistance. FOXM1 is a potent oncogenic factor essential for cancer …
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WebRecognizes human FOXM1b, C-terminal. Suitable for Immunohistochemistry and Immunoprecipitation applications. Forkhead box protein M1 is a member of the FOX family of proteins involved in gene expression specifically transcription factors. It is an important protein in cell cycle where endogenous FOXM1 expression peaks at S and G2/M phases.
WebNov 15, 2002 · Maintaining FoxM1B expression in regenerating liver of old-aged TTR-FoxM1B TG mice is sufficient to increase hepatocyte DNA synthesis and mitosis to levels found in young (2-month-old) regenerating mouse liver (18). Furthermore, FoxM1B-mediated stimulation of hepatocyte proliferation was associated with increased … tax assessor harwich maWebSep 25, 2001 · Furthermore, FoxM1B provided a 2.8-fold induction in cyclin D1 promoter expression in HepG2 cell cotransfection assays (Fig. 5). These studies demonstrated that FoxM1B is able to transcriptionally activate the cyclin B1 and cyclin D1 promoters, suggesting that FoxM1B functions to directly regulate transcription of these cyclin genes. tax assessor harris county txWebThe delayed early transcription factor Forkhead Box M1B (FoxM1B) is expressed in proliferating cells, but its expression is extinguished in cells undergoing terminal differentiation. Liver regeneration studies with genetically altered mice that either prematurely expressed FoxM1B in hepatocytes or contained a hepatocyte-specific … tax assessor hardin county tnWebOct 22, 2009 · Here we report that Foxm1b is the first direct farnesoid X receptor (FXR) target gene known to be involved in cell cycle regulation and that aging regenerating livers have delayed activation of FXR, which results in defective induction of Foxm1b and thereby contributes to defective liver regeneration. An inverted repeat 0 (IR-0) FXR response ... tax assessor hamilton county tennesseeWebFOXM1 Antibodies Antibodies that detect FOXM1 can be used in several scientific applications, including Western Blot, ELISA, Immunocytochemistry, Immunohistochemistry and ChIP. These antibodies target FOXM1 in Human, Mouse and Rat samples. tax assessor harrison county msWebJun 11, 2024 · E and G Lysates of S2-CP8 cells stably expressing control shRNA, FOXM1 shRNA, or FOXM1 shRNA and T7-FOXM1b ( E) and Capan-1 cells stably expressing control vector, FLAG-FOXM1c, or FLAG-FOXM1cΔNLS ( G) were probed with the indicated antibodies. Clathrin was used as a loading control. the chalet tea rooms portinscaleWebfkhl16, foxm1b, hfh-11, hfh11, hnf-3, ins-1, mphosph2, mpp-2, mpp2, pig29, tgt3, trident the chalet portinscale keswick