Micafungin 300 mg twice weekly
WebbC-micafungin was added to whole human blood, the blood to plasma ratio was approximately 0.85 and was independent of concentration over the range of 0.1 to 10 µg/mL micafungin. Micafungin was not extensively taken up by blood cells. The volume of distribution of micafungin at terminal phase was 0.24 to 0.41 L/kg body weight. … WebbMETHODS: Twice-a-week micafungin at a dose of 9 mg/kg (maximum 300 mg) was given during the leukaemic induction treatment with at least one pharmacokinetic assessment. Non-linear mixed-effects modelling was used for analysis. For model building, our paediatric data were strengthened with existing adult data.
Micafungin 300 mg twice weekly
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WebbThe preferred initial treatment is an echinocandin ( micafungin 100 mg intravenously [IV] daily; anidulafungin 200 mg loading dose, then 100 mg IV daily; or caspofungin …. … Webb¥ Our preferred dosing of echinocandins in adults with esophagitis is as follows: anidulafungin 200 mg IV daily; caspofungin 70 mg daily; or micafungin 150 mg IV …
WebbIn an in vitro model of a C. albicans, biofilm associated with silicone catheters, caspofungin (2 mg/L), and micafungin (5 mg/L) used as lock solutions were able to reduce the … Webb8 aug. 2024 · An intermittent dosing strategy in adults with a high risk of fungal infection using a twice-weekly dose of 300 mg is ongoing (ClinicalTrials.gov …
WebbEnter the email address you signed up with and we'll email you a reset link. WebbAnswer: Micafungin in neonates is given at 10 mg/ kg/day, which is considerably greater than in children (2 mg/kg/day) and due to the very fast clearance of the drug in neonates. Answer: Caspofungin in youngsters is dosed based mostly on a body-surface area method, loading with 70 mg/m2 on day 1 after which continuing with 50 mg/m2 as maintenance …
Webb1 dec. 2015 · a Eleven patients received 300 mg of micafungin twice and/or once weekly before, after, or during the administration of 300 mg 3 times weekly: 5, 1, 1, and 1 …
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