WebSep 26, 2024 · Myotonic dystrophy type 1 (DM1) and myotonic dystrophy type 2 (DM2) are autosomal dominant, multisystem disorders characterized by skeletal muscle weakness and myotonia, cardiac conduction abnormalities, iridescent cataracts, and other abnormalities. The management and prognosis of patients with DM will be reviewed here. WebMyotonia (delayed muscle relaxation after contraction) is often described by patients as muscles ‘locking’, ‘sticking’ or ‘cramping’. Episodic weakness can vary significantly from one limb ‘not working or feeling right’ to a tetraparesis.
Myotonic dystrophies type 1 and 2: anesthetic care - PubMed
WebMyotonic dystrophies type 1 and 2: anesthetic care Myotonic dystrophy is classified as one of the myotonic syndromes although myotonia is only a minor characteristic of it. It is, in fact, also a multisystem disease with cardiac, digestive, ocular, and endocrine abnormalities. WebResearchers used a genetic therapy involving antisense oligonucleotides to restore muscle strength and correct myotonia, or muscle stiffness, in mice with myotonic dystrophy. The findings indicate that targeted treatments may reverse myotonia and benefit patients with myotonic dystrophy. BOSTON – People with myotonic dystrophy experience ... rao advisors
IJMS Free Full-Text Non-Coding RNAs in Muscle Dystrophies
WebMar 20, 2024 · Maintenance of anesthesia with total intravenous anesthesia avoids volatile anesthetics which often cause shivering and hence precipitate myotonia. We used … WebMuscle disorders linked to anesthetic complications include malignant hyperthermia (MH), central core disease, muscular dystrophy, periodic paralysis (hyper- and hypokalemic), … WebAnesthesia and myotonic dystrophy (DM1) Preoperative period: Preoperative evaluation of patients with DM should involve a multidisciplinary team including medical, neurology, cardiac, and anesthesiology specialties. Any preoperative weakness should be addressed and further evaluated. rao5s.vn