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WebChimeric mice with humanized liver are thought to represent a sustainable source of isolated human hepatocytes for in vitro studying detoxification of drugs in humans. Because drug transporters are now recognized as key-actors of the hepatic detoxifying process, the present study was designed to cha … WebHealth Report. The reconstituted 'humanized liver' in TK-NOG mice is mature and functional. Human biofluid concentrations of mono (2-ethylhexyl)phthalate extrapolated from …
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