WebMay 5, 2006 · Fat tissue is the most important energy depot in vertebrates. The release of free fatty acids (FFAs) from stored fat requires the enzymatic activity of lipases. We showed that genetic inactivation of adipose triglyceride lipase (ATGL) in mice increases adipose mass and leads to triacylglycerol deposition in multiple tissues. WebAdipose triglyceride lipase (ATGL) is a recently described adipose-enriched protein with triglyceride-specific lipase activity. ATGL shares the greatest sequence homology with …
Triacylglycerol lipases and metabolic control: implications for …
WebNov 6, 2024 · Adipose triglyceride lipase (ATGL) is an enzyme that plays a critical role in the mobilization of stored triacylglycerol. Despite its importance in lipid metabolism, in-depth biochemical characterization of ATGL has been limited because the expression and purification of this enzyme are not feasible. In this study, we attempted to generate the … WebAug 1, 2010 · Fatty acids derived from the hydrolysis of adipose tissue and skeletal muscle triacylglycerol (TG) are an important energy substrate at rest and during physical activity. This review outlines the identification of the new TG lipase, adipose triglyceride lipase, the current understanding of how cellular TG lipases are regulated, and the implications for … horoscope for august 1 2022
A rationally engineered specific near-infrared fluorogenic …
WebThe Triglyceride-Glo™ Assay detects triglyceride levels by measuring glycerol that is released from an enzymatic reaction with a lipase: one mole of glycerol per mole of triglyceride. Glycerol is measured in a coupled reaction scheme that links the production of NADH to the activation of a proluciferin that produces light with luciferase. The amount of … WebDeletion of adipose triglyceride lipase abolishes blood flow increase after β3-adrenergic stimulation in visceral adipose tissue of mice. / Lee, Hye Jin; Jin, Bo Yeong; Park, Mi Rae et al. In: Korean Journal of Physiology and Pharmacology, Vol. 25, No. 4, 07.2024, p. 355-363. Research output: Contribution to journal › Article › peer-review WebGene Ontology Term: triglyceride lipase activity. Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate. amano AP, amano B, amano CE, amano CES, amano … horoscope for birthday on march 1